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steve kirsch fluvoxamine
The ICER independent review showed fluvoxamine is more effective than Molnupiravir: Read this article I wrote about using fluvoxamine correctly for COVID. We dont want to feed the anti-vaccine trolls, so we actively suppress clear scientific data. The U of M's study focused on three common drugs: ivermectin, metformin, and fluvoxamine. The man who ran Risperdal sales, Alex Gorsky, is now CEO of Johnson & Johnson. this is NOT about the science. I've collected fluvoxamine evidence here for convenient access. 19 In addition, several . Most recent articles first. That trial has now been completed, and the researchers are analyzing their data. Dose escalation studies in lupus patients and in rheumatoid arthritis patients established that 800 mg per day for life and 1,200 mg per day for 6 weeks are extremely well-tolerated. Drug interactions should be checked for. No more. The WashU Phase 3 study hasnt been disclosed yet, but they had compliance problems with their patients this time around (phase 2 was local so the patients got the drug early and also were very compliant and the placebo group was truly taking nothing). Ivermectin has been falsely promoted as a covid treatmentbut for those who use the drug legitimately, seeing it become a piece of anti-vaccine misinformation is disconcerting. This is what the Seftel trial at Golden Gate fields used. When you need to characterize me, you need to say that Steve Kirsch doesnt go with majority votes on interpreting data, he told me when I asked about his views on ivermectin, which he insists is a silver bullet against covid. That receptor also helps regulate the body's . No long haul symptoms if you start the drug ASAP after first symptoms. Doctors wait for government permission (EUA or added to the NIH guidelines) before using a drug. He said of his study, This is the most extraordinary effect Ive seen in my 25 years practicing medicine.. It has enrolled only 130 people in the first month and is enrolling only 70 per week now. It doesnt get much better than that. It was tested in. In October, the group reported that, while a few patients in the placebo group ended up in the hospital, none of the patients receiving fluvoxamine got sick enough to go. On January 22, 2021, thirty key opinion leaders (KOL) from NIH, CDC, and leading academic institutions met to review the evidence for using fluvoxamine for treating COVID. As of November 13, fluvoxamine has been proven to work in every trial that has published results, including outpatient and inpatient studies. Both drugs have compelling data that is hard to explain if the drug doesn't work. Fluvoxamine at 50mg twice a day for 14 days is a very well-tolerated drug (as long as you avoid caffeine and alcohol) for the treatment of COVID infections. This drug can save your life but you have to ask for it! Kirsch, despite having direct access to the actual trial runner, eventually became convinced a correct interpretation of the data would show that hydroxychloroquine worked. Dosage there is 30mg once a day. At the end of May this year, Siliciano emailed the other advisors to say that Kirsch had gone off the deep end and he was cutting ties. It used to be that a Phase 3 study would do it. Why the FDA should grant an EUA for fluvoxamine immediately, a brilliant op-ed in the Wall Street Journal, "Too much caution is killing COVID patients. Fluvoxamine is the poster child of the COVID-19 Early Treatment Fund (CETF). Entrepreneur Steve Kirsch who holds an early patent for the optical mouse decided to get involved in treating Covid. All this was known back in January 2021 when a key opinion leader panel of experts from NIH, CDC, FDA, academia, and journal editors voted by over 2:1 to recommend that fluvoxamine be recommended to physicians to discuss with patients. It was tested in coronavirus patients because fluvoxamine has very strong anti-inflammatory properties. The drugs mechanisms of action were explained to the KOL panel which voted 2>1 in favor of fluvoxamine. Independent appraisal committee votes 11-2 that the evidence is not adequate to demonstrate a net health benefit for molnupiravir over symptomatic care alone; Paxlovid and fluvoxamine receive more favorable votes. We should be making decisions now based on the evidence on the table today. I will . And that is what has allowed Kirsch, and people like him, to become so influential. Compulsive hand washing? Steve Kirsch is an inventor of the optimal mouse, a Silicon Valley millionaire, and an MIT alum (Class of '80). Or just depression about the vaccine mandates? The most stunning study of fluvoxamine ever done was at the Golden Gate Fields racetrack in November 2020, right after the WashU trial was published in JAMA. . - Quora, Heres presentation I gave at the re-open California Conference on January 9,2021: How to fix the problemHow to fix the problem Steve Kirsch Executive DirectorCOVID-19 Early Treatment Fund stk@treatearly.org 650-279-1008Google Docs[https://docs.google.com/presentation/d/1-A4y78wv3tTPmVu57FOabY6j-MJbPwMGojKwZfaCkAs/. He was recently featured on 60 Minutes which highlighted his . The effect size is huge if the drug is given early right after symptoms start. This post was written to memorialize the corruption. The Lancet paper showed that if you were treated early enough and took the drug as prescribed (it only works if you take it), it was shown to reduce your chance of death by 12X making it far more effective than any other drug for COVID. Think about it Molnupiravir has a 50% risk reduction whereas fluvxoamine is over 90%. Thats pretty typical, but your mileage may vary. Kirsch did a lot of things right when he set up CETF. Steve Kirsch is a high-tech serial entrepreneur based in Silicon Valley. Online. So take the lowest likely effect size * 60% success rate and you are looking at an expected 45% reduction in death which is clearly better than a 0% reduction. So you can address your OCD and if you get COVID, youll can up the dose. Over the summer, the conflict reached his most recent startup, M10. So instead of this paper being treated as confirming an earlier hypothesis, it was treated as generating a novel hypothesis. Fluvoxamine works on hospitalized patients too, but no US hospital will let you use it (sound familiar? Although there is evidence that fluvoxamine can prevent clinical worsening and the need for hospitalizations in outpatients with early covid-19, I have seen no good evidence that fluvoxamine is useful as a substitute for the vaccines, co-investigator Angela Reiersen wrote to me. According to its founder, serial tech entrepreneur Steve Kirsch, CETF was started in April 2020 in order to fund. He is frequently brash and interruptive, peppering dire warnings about vaccines with veiled aspersions toward Anthony Fauci and vague references to influential people who agree with him in private but cannot speak publicly. . Fluvoxamine has a 40 year safety track record. YouTube , , , fluvoxamine, , , , , , , , , , In it, he claimed mRNA vaccines kill one in 5,000 recipients and dramatically increase the rate of miscarriages. The NIH wrote a bullshit rejection because the FDA told them not to approve it. I couldn't agree more. Today, we are letting people drown and we are not even telling them there is a life preserver they can ask for today with compelling evidence that is under consideration by the life preserver safety group. Vitamin D, NAC, betadine, aspirin, and Nigella sativa are all super cheap, effective, and available without a prescription. It is an amazing drug and is a very simple safe way to avoid long-haul COVID symptoms. Who knows, Morris replied. Soon after his appearance on the DarkHorse podcast, several partners of his most recent startup, M10, expressed concerns about the increasing extremism of Kirschs vaccine views. The drugs mechanisms of action were explained to the KOL panel which voted 2>1 in favor of fluvoxamine. It was 25 years ago yesterday that Andrew Wakefield launched the modern iteration of the antivaccine movement.In doing so, he laid down a template that antivax quacks today still follow. Every earlier study of fluvoxamine (such as observational studies) showed it work and the mechanism had been shown. You can experience serious side effects if you do not pay attention to interactions such as if you are currently on another SSRI of a different type. Its all about NIH saying it is OK. Medicine today is driven by government opinion, not science. Sadly, doctors and public health officials refuse to instruct patients to seek early treatment. CETF Founder Steve Kirsch discusses why we can't wait for a COVID-19 vaccine, the importance of researching existing drugs now, and our work to raise funds for outpatient trials to identify effective . That was a lie. ICER Publishes Final Evidence Report and Policy Recommendations on Outpatient Treatments for COVID-19 - ICER. Kirsch said that his attempts to promote fluvoxamine are being curtailed. That way you can start immediately. Or just depression about the vaccine mandates? Several former members told me he began relentlessly pressuring them to promote the drug in media stories, often during exhausting, circuitous conversations. Fluvoxamine is also an We are ignoring the advice of the KOL group and doing nothing. Steve Kirsch is a Silicon Valley philanthropist. I also think it makes a lot of sense to look for pre-existing drugs that can help treat covid symptoms. Online. From the French observational data (see the very last page), it appears that the biggest effect is limiting serotonin release (any SSRI will do that). And, according to three members of CETF's scientific advisory board, he put pressure on them to promote fluvoxamine for clinical use without conclusive data that it worked for . All the supporting observational studies were positive as well. CETF funded David Boulware's trials on hydroxychloroquine and the Phase 2 and Phase 3 fluvoxamine trials, among many other research projects. Were having trouble saving your preferences. If you have trouble getting a prescription, perhaps you have OCD? Kirsch is a serial entrepreneur who has spent decades pitching the next big thing, whether optical mice (Mouse Systems), document processing (FrameMaker), search engines (Infoseek), digital security (OneID), or e-commerce (Propel Software). They knew in advance it was coming and on the day the paper was published they ignored it entirely. Steve wanted to say, Look, Ive got all these famous [infectious disease] docs and researchers, and they all say give fluvoxamine a chance, Judith Feinberg, one of the former CETF advisory board members and vice chair of research at the West Virginia University School of Medicine, told me. After I ended the Zoom meeting, Satterfield called me to apologize for cutting us off. BOMBSHELL: Top biostats professor admits we have NO CLUE # of people KILLED by COVID vaccines, he wrote. He has been a medical philanthropist for more than 20 years. In that same IEEE Spectrum story about his then-new startup, Propel Software, he said he felt successful, but not famous. Nobody in the medical community is speaking out about how hypocritical the medical community is for ignoring the positive Phase 3 trial results and instead following whatever the NIH or FDA says. The collateral damage is that, now, a lot of people dont trust scientific leaders or the scientific community. Medium revoked my account for life. I must admit that this is an anniversary that snuck Why not fluvoxamine? See this Wall Street Journal op-ed. Added to FLCCC protocols and Fareed-Tyson protocol among others. We have a bounty of vaccines and more on the way, but drugs that treat the disease are vital too if we want to keep people alive and bring the pandemic under control. NIH doesnt want you to get the drug since it would compete with Molnupiravir, so fluvoxamine will never make the NIH guidelines. Three of the four outpatient trials have been reported out: all were successful. If the drug is started right after symptoms, weve seen 100% prevention in hospitalization. It used to be that a Phase 3 study would do it. We should not wait for the Phase 3 RCT. Fluvoxamine, COVID, pandemic, . Pretty much nothing changed when the Phase 3 trial confirmed fluvoxamine worked. Steve Kirsch: Vaccine Killing Millions, Treatments, VAERS, 5-Month Death Signal, Mystery Clots Embed 1.15K 'This Has Cost Millions of Lives': Steve Kirsch on Suppression of Repurposed Drugs and a Spike in Deaths 5 Months After Vaccine Rollout American Thought Leaders AMERICAN THOUGHT LEADERS JAN JEKIELEK Show more Loading comments. Even though an expert panel was overwhelmingly convinced in just one hour, hearing a very small subset of all the supporting evidence, the organizations that they belong to are taking their time. Fluvoxamine works on hospitalized patients too, but no US hospital will let you use it (sound familiar? Boulwares trial was part of a wider movement to bulk up the evidence base underlying standard covid treatments, and one of several trials that found no benefit to using hydroxychloroquine. In three phone conversations, as well as dozens of emails, his responses to questions about claims in this story were imprecise or constantly changing. If it isn't fluvoxamine preventing hospitalization and long-haul COVID, then if you find what it is, you win. There is no evidence fluvoxamine is harmful and led to a worse outcome. Silence from the medical community. In September, Kirsch emailed Morris asking him to estimate the maximum number of deaths caused by vaccines. Molnupiravir followed patients for only 30 days because they know the drug is dangerous. To date, we have heard nothing suggesting the drug doesn't work or could be harmful. Medicine isnt about saving lives anymore. Seftel was able to duplicate the 100% protection from hospitalization and death in the treatment group, vs. a 12.5% hospitalization/death rate for the No treatment group. The premise made sense: Most experts were predicting vaccines would take years, while finding helpful drugs with known safety profiles could shortcut the approval process. By Steve Kirsch in fluvoxamine Feb 14, 2021 The case for fluvoxamine for treating COVID-19 A very short op-ed arguing for using fluvoxamine against COVID. Eventually, a press representative who was listening in, David Satterfield, unmuted his microphone to suggest we finish our conversation by email. He applied the drug to a large COVID outbreak at Golden Gate Fields just days after the Lenze trial was published. Skirsch.io Steve Kirsch Home page Fluvoxamine, COVID, pandemic, . The 50mg BID dose was quite effective, but it has to be started early (as soon as symptoms start). This is a more comprehensive look at the key evidence supporting fluvoxamine: Hear from the doctors who did the studies directly as well as the Dean of Medicine at Emory University: List of the best evidence-based COVID treatment options. They were all given the drug soon after symptoms and the placebo group was pure in that they were not taking any COVID drugs. Its board told him that if he wanted to remain part of the company he would have to stop making public anti-vaccine statements. My publicly shared concerns regarding the safety of the COVID-19 vaccines may have had a negative impact on my company, M10. In-patient use. Always be self aware when using fluvoxamine. With cases spiking, the Los Angeles area banned gatherings. If you ask your doctor for any evidence that fluvoxamine doesnt work or is harmful (like a DB-RCT which is the only thing they trust), they will show you nothing. Fluvoxamine has a 40 year safety track record. His efforts became more focused on medical research when, in 2007, he was diagnosed with a rare blood cancer. So how did a man once intent on furthering science become a source of misinformation that undermines the very research he funded? It cant be more clear than this. ICER: Some speaker, off camera, went on a . more time. The reason is pure corruption. To protect M10 from my COVID-19 vaccination opinions, I will no longer post about my vaccination concerns here.. P-value was 10^-14 on that study (done by Dr. Seftel). Fluvoxamine (Luvox) is a Selective Serotonin Receptor Inhibitor (SSRI) that is clinically indicated for OCD in children, and can be used off label for depression. The NIH picks the drug that makes the most money for the drug companies regardless of long-term safety Molnupiravir! This was shown to be very tolerable (no side effects in 99% of patients) and extremely effective (no hospitalizations and death if you start it ASAP after first symptoms). It is very safe: There is no evidence fluvoxamine is harmful and led to a worse outcome. Those days are gone. Quick Summary . The CDC has advised everyone to wear a mask. P-value was 10^-14 on that study (done by Dr. This advice is now outdated. For example, tylenol+caffeine+fluvoxamine can lead to serotonin syndrome. In fact, he was unwittingly the source for one of Kirschs figures. Personal life. In a recent post, discussing claims Kirsch made during a three-minute comment at an FDA public forum, Morris wrote: In spite of many pages of writing and claims of over a dozen independent analyses verifying their results, their evidence falls far short of substantiating these dramatic conclusions, including a claim that vaccines have caused >250K excess deaths in the USA.. In some cases, youd want to taper down the dosage. This is the gold standard of evidence based medicine. They were giving covid patients the antidepressant fluvoxamine as soon as possible after diagnosis, based on anecdotes about the drug limiting the runaway immune response that causes many severe symptoms. Kirsch and his group received a fresh wave of attention off hopeful trials of the antidepressant fluvoxamine, which ultimately won him a spot on 60 Minutes in March. Enter the email address you signed up with and we'll email you a reset link. We now have a viable solution to reduce COVID hospitalization and mortality; Say you just got diagnosed with COVID. Where did it go wrong. Thats pretty typical, but your mileage may vary. Timing is everything with respect to outcomes. Doctors who have used fluvoxamine in the US and other countries swear by it. Fluvoxamine is a very safe drug on market for 37 years, tens of millions of people have taken it, no record in scientific literature of anyone dying on overdose, and according to doctors that know the drug the best, about as dangerous as taking a Tylenol. Steve Kirsch: Vaccine Killing Millions, Treatments, VAERS, 5-Month Death Signal, Mystery Clots Embed 7.76K 31 'This Has Cost Millions Of Lives': Steve Kirsch On Suppression Of Repurposed Drugs And A Spike In Deaths 5 Months After Vaccine Rollout By Jan Jekielek American Thought Leaders / The Epoch Times November 24, 2022 Show more Note that some of these articles are inaccurate. Mar. . The study was also featured on 60 Minutes. Steve Kirsch -Executive Director at COVID-19 Early Treatment Fund Ivermection study - One .2mg/kg dose a week for prevention "100% success rate whereas those doctors taking placebo had a 59%% infection rate not a typo 237 of 400 docs on placebo got infected vs. 800 docs on Ivermectin none got infected" Antivirals . Generally, at 50mg BID x 14, it is very tolerable as long as the patient is instructed to lay off the caffeine. Thirty minutes past the end of our scheduled time, he dropped his phone in the cupholder of his Tesla so that he could keep talking while he ran an errand. They left their recommendation of fluvoxamine at NEUTRAL. There are at least eight mechanisms of action that we think contribute to the effectiveness of this drug. The NIH never did a risk benefit analysis of this drug. Yes, these were successes, but the successes could have been bigger if we had really paid attention to marketing. It has shown to be 100% protective of hospitalization in 2 clinical trials. 533. Fluvoxamine has a systematic review and meta-analysis published in a top medical journal. Even though they spent only 45 minutes and just reviewed the 2 clinical studies and some plausible mechanisms of action (and ignored anecdotal evidence and multiple retrospective trials, all of which were supportive), after the meeting they voted overwhelmingly (11 to 5 with 4 being neutral) in favor of having doctors talk to their patients about using fluvoxamine if they have COVID using a "shared decision making" process. Have the drug on hand. They were all given the drug soon after symptoms and the placebo group was pure in that they were not taking any COVID drugs. If you are experiencing any odd adverse reactions, youll need to consult with your doctor ASAP. This is the #1 ranked best answer to "COVID treatment" on Quora: Presentation on how fear of trying something new is what keeps us shutdown and leads to unnecessary loss of life: The Lenze fluvoxamine RCT that was published in JAMA on November 12, 2020 showed a 100% success rate in preventing hospitalization. He told me that while he and his family got vaccinated as soon as they were eligible, he got the idea that vaccines are dangerous from a man he hired to clean his carpets, who got very sick after receiving the vaccine. The. In June, after CETFs advisory board resigned, Kirsch did a Facebook Live video with Zelenko and celebrity rehab coach Dr. Drew. CETF was founded by entrepreneur and philanthropist Steve Kirsch, as a way to expedite the fight against COVID-19. Nobody who took the drug got sick at all, most all wanted to return to work within 3 days after starting treatment. The infectious disease scientists lied to me. . Fluvoxamine is a well-tolerated, widely available, inexpensive selective serotonin reuptake inhibitor that has been shown in a small, double-blind, placebo-controlled, randomized study to prevent clinical deterioration of patients with mild coronavirus disease 2019 (COVID-19). You can help by bringing this document to your doctor's attention. Hes also recently increased the number of Americans he claim have been killed by the vaccine from 25,0000, to 150,000, or even as many as 250,000 Americans. As trial results rolled in, that mismatch began to put a strain on Kirschs relationship with the funds advisory board. It is about following orders and making money for the drug companies and protecting the doctor from liability and losing his medical license. Get your prescription in advance of getting COVID. Kirsch and his wife, Michele, fund a charitable foundation, which by 2007 had given $75 million to different causes. Everyone says "we need more data" to show fluvoxamine works for COVID. Some people are jittery, but usually that is because the doctor either prescribed a dosage higher than 50mg twice a day or didnt notify the patient to completely avoid the list in the previous paragraph, or the patient is simply sensitive to the drug (50mg twice a day can be too much for some people).
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